Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537348 | 0.83 | MAPK1 (0.44) | VKORC1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL28537368 | 0.78 | KDM4E (0.45) | KDM4EMAPK1MEN1KMT2ACYP2C9 | |
| SCHEMBL28530799 | 0.76 | NQO1 (0.48) | KDM4EMAPK1NQO1CA1CA2 | |
| SCHEMBL28531260 | 0.76 | KDM4E (0.42) | VKORC1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL9496068 | 0.76 | TYR (0.52) | VKORC1KDM4ETYRMEN1KMT2A | |
| SCHEMBL28534246 | 0.75 | NQO1 (0.47) | KDM4EMAPK1MEN1KMT2ACYP2C9 | |
| SCHEMBL28534244 | 0.75 | TOP2A (0.39) | KDM4EMAPK1MEN1KMT2ANQO1 | |
| SCHEMBL28539636 | 0.75 | TOP2A (0.39) | KDM4EMAPK1MEN1KMT2ANQO1 | |
| SCHEMBL28529758 | 0.75 | MAPT (0.53) | KDM4EMAPK1MEN1KMT2ANQO1 | |
| SCHEMBL6174518 | 0.74 | VKORC1 (0.55) | VKORC1TYRMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112517060-B | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112517060-A | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2021-03-19 | — | — | CN | disclosed |