Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530348 | 0.89 | ALOX5AP (0.48) | ALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL28540938 | 0.89 | PDE10A (0.49) | ALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL28546238 | 0.83 | ALOX5AP (0.48) | ALOX5APPDE10ACYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL28523720 | 0.74 | PDE10A (0.47) | ALOX5APPDE10ACYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL28535273 | 0.71 | PDE10A (0.48) | ALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL28910779 | 0.71 | PDE10A (0.47) | ALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL28907986 | 0.71 | PDE10A (0.51) | PDE10ACYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10510977 | 0.70 | CYSLTR1 (0.69) | PDE10ACYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6454291 | 0.66 | HTT (0.42) | ALOX5APPDE10A | |
| SCHEMBL10686237 | 0.65 | PDE10A (0.68) | PDE10ACYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384766-B | Quinoline compound and preparation method and application thereof | 广东环境保护工程职业学院 | 2021-02-09 | — | — | CN | disclosed |