Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 11/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910779 | 0.92 | PDE10A (0.47) | PDE10AALOX5APCYSLTR2CYSLTR1 | |
| SCHEMBL28546238 | 0.88 | ALOX5AP (0.48) | PDE10AALOX5APCYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL28540938 | 0.82 | PDE10A (0.49) | PDE10AALOX5APCYSLTR2CYSLTR1 | |
| SCHEMBL28907986 | 0.76 | PDE10A (0.51) | PDE10ACYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL28526465 | 0.76 | PDE10A (0.46) | PDE10AALOX5APCYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL28530348 | 0.74 | ALOX5AP (0.48) | PDE10AALOX5APCYSLTR2CYSLTR1 | |
| SCHEMBL28530346 | 0.71 | ALOX5AP (0.49) | PDE10AALOX5APCYSLTR2CYSLTR1 | |
| SCHEMBL27816005 | 0.69 | CYSLTR1 (0.64) | PDE10AALOX5APCYSLTR2CYSLTR1 | |
| SCHEMBL6449871 | 0.68 | HTT (0.42) | PDE10AALOX5APCYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL8881140 | 0.67 | CYSLTR1 (0.55) | PDE10ACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384766-B | Quinoline compound and preparation method and application thereof | 广东环境保护工程职业学院 | 2021-02-09 | — | — | CN | disclosed |