Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 10/20 | 0.55 |
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944384 | 1.00 | DYRK1A (0.55) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL30944419 | 0.88 | RAB9A (0.56) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL30944383 | 0.88 | DYRK1A (0.56) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL31236381 | 0.88 | NPC1 (0.66) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL30944425 | 0.87 | NPC1 (0.67) | DYRK1ANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30944301 | 0.86 | DYRK1A (0.58) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL30944318 | 0.86 | DYRK1A (0.58) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL28530647 | 0.86 | DYRK1A (0.58) | DYRK1ANPC1RAB9ACNR1CLK1 | |
| SCHEMBL30944393 | 0.86 | CNR1 (0.71) | DYRK1ANPC1RAB9ACNR1SMN1; SMN2 | |
| SCHEMBL30944298 | 0.85 | NPC1 (0.61) | NPC1RAB9ACNR1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | disclosed |