Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 9/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530647 | 1.00 | DYRK1A (0.58) | DYRK1ACYP2D6CSNK1DACP1NPC1 | |
| SCHEMBL30944318 | 1.00 | DYRK1A (0.58) | DYRK1ACYP2D6CSNK1DACP1NPC1 | |
| SCHEMBL28520781 | 0.92 | DYRK1A (0.58) | DYRK1ACYP2D6CSNK1DACP1NPC1 | |
| SCHEMBL30944359 | 0.92 | DYRK1A (0.58) | DYRK1ACYP2D6CSNK1DACP1NPC1 | |
| SCHEMBL31236381 | 0.87 | NPC1 (0.66) | DYRK1ANPC1RAB9ACNR1LRRK2 | |
| SCHEMBL30944285 | 0.86 | DYRK1A (0.60) | DYRK1ACYP2D6CSNK1DACP1NPC1 | |
| SCHEMBL28530536 | 0.86 | DYRK1A (0.60) | DYRK1ACYP2D6CSNK1DACP1NPC1 | |
| SCHEMBL30944384 | 0.86 | DYRK1A (0.55) | DYRK1AACP1NPC1RAB9ACNR1 | |
| SCHEMBL28530631 | 0.86 | DYRK1A (0.55) | DYRK1AACP1NPC1RAB9ACNR1 | |
| SCHEMBL30944399 | 0.86 | NPC1 (0.49) | DYRK1ACYP2D6CSNK1DNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |