SCHEMBL28530801

SCHEMBL28530801

CC[C@H](C)N[C@@H](C)Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.63
TAAR1 Q96RJ0 3/20 0.61
SLC18A2 Q05940 1/20 0.61
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
TSHR P16473 1/20 0.52
TRPA1 O75762 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28530803 1.00 SIGMAR1 (0.63) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL28534586 1.00 SIGMAR1 (0.63) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL21243273 0.91 SIGMAR1 (0.73) SIGMAR1TAAR1SLC18A2MEN1KMT2A
Diphenylmethane SCHEMBL23578508 0.85 CALM1 (0.52) SIGMAR1TAAR1SLC18A2CYP3A4CYP2D6
SCHEMBL20822465 0.84 SIGMAR1 (0.59) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL5072576 0.83 SIGMAR1 (0.68) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL25589819 0.83 SIGMAR1 (0.68) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL5072573 0.83 SIGMAR1 (0.68) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL10537675 0.82 SIGMAR1 (0.50) SIGMAR1TAAR1SLC18A2MEN1KMT2A
Hydrochloric Acid SCHEMBL7037524 0.81 SIGMAR1 (0.66) SIGMAR1TAAR1SLC18A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500429-B Preparation method of Reidesciclovir intermediate 东南大学 2022-04-12 CN disclosed
CN-112500429-A Preparation method of Reidesciclovir intermediate 东南大学 2021-03-16 CN disclosed