Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.48 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516905 | 0.88 | MET (0.39) | METCHRM4 | |
| SCHEMBL28529522 | 0.86 | MET (0.49) | METKDRRETKITPDGFRA | |
| SCHEMBL28907382 | 0.86 | MET (0.44) | METKDRRETKITPDGFRA | |
| SCHEMBL29728994 | 0.81 | MET (0.45) | METKDRRETKITPDGFRA | |
| SCHEMBL19987751 | 0.81 | MET (0.45) | METKDRRETKITPDGFRA | |
| SCHEMBL23754947 | 0.80 | MET (0.39) | METKDRRETKITPDGFRA | |
| SCHEMBL30086269 | 0.80 | MET (0.39) | METKDRRETKITPDGFRA | |
| SCHEMBL3555808 | 0.79 | MET (0.54) | METKDRRETKITPDGFRA | |
| SCHEMBL1794164 | 0.79 | TRPA1 (0.58) | METKDR | |
| SCHEMBL3556668 | 0.79 | MET (0.52) | METKDRRETKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793363-B | Substituted arylamino aromatic heterocyclic compound and application thereof as antitumor drug | 上海医药工业研究院 | 2021-02-26 | — | — | CN | disclosed |