Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1323012 | 0.85 | APEX1 (0.58) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL28026431 | 0.85 | ALDH1A1 (0.44) | ALDH1A1PTGDR2MAOASTAT3MAPT | |
| SCHEMBL21666210 | 0.83 | ALDH1A1 (0.64) | ALDH1A1STAT3MAPTMEN1POLB | |
| SCHEMBL3529308 | 0.83 | STAT3 (0.48) | ALDH1A1STAT3MAPTMEN1POLB | |
| SCHEMBL796957 | 0.83 | ALDH1A1 (0.73) | ALDH1A1PTGDR2MAOAMAPTMEN1 | |
| SCHEMBL21199639 | 0.81 | ALDH1A1 (0.45) | ALDH1A1STAT3MAPTMEN1POLB | |
| SCHEMBL21198945 | 0.81 | ALDH1A1 (0.60) | ALDH1A1STAT3MAPTMEN1POLB | |
| SCHEMBL25014735 | 0.81 | ALDH1A1 (0.44) | ALDH1A1STAT3MAPTMEN1POLB | |
| SCHEMBL21453742 | 0.81 | ALDH1A1 (0.44) | ALDH1A1STAT3MAPTMEN1POLB | |
| SCHEMBL18988716 | 0.80 | STAT3 (0.53) | ALDH1A1PTGDR2MAOASTAT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071498-B | Kinase inhibitor and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-03-30 | — | — | CN | disclosed |