Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850703 | 0.91 | CNR1 (0.56) | SMN1; SMN2CNR1LMNAKMT2AALDH1A1 | |
| SCHEMBL2859857 | 0.90 | CNR1 (0.55) | SMN1; SMN2CNR1LMNAKMT2AALDH1A1 | |
| SCHEMBL2880891 | 0.81 | CNR1 (0.54) | SMN1; SMN2CNR1LMNAKMT2AKDM4E | |
| SCHEMBL2860983 | 0.80 | MAPT (0.49) | SMN1; SMN2LMNAKMT2AALDH1A1EPHX2 | |
| SCHEMBL2858063 | 0.80 | MAPT (0.57) | SMN1; SMN2LMNAALDH1A1KDM4EMAPT | |
| SCHEMBL2862263 | 0.79 | MAPT (0.47) | CNR1LMNAALDH1A1KDM4EMAPT | |
| SCHEMBL2856146 | 0.79 | CNR1 (0.53) | SMN1; SMN2CNR1LMNAKMT2AALDH1A1 | |
| SCHEMBL2872664 | 0.78 | MALT1 (0.42) | MAPT | |
| SCHEMBL2854478 | 0.78 | ITGB3 (0.46) | SMN1; SMN2LMNAKMT2AMAPTGAA | |
| SCHEMBL2856795 | 0.78 | NPC1 (0.46) | CNR1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |