SCHEMBL2853254

SCHEMBL2853254

CCC1C(=O)N(CC)C(=O)N(CC)C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.57
ELANE P08246 1/20 0.57
CTSG P08311 1/20 0.57
CTRC Q99895 1/20 0.57
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
GMNN O75496 1/20 0.39
MAPT P10636 1/20 0.39
THPO P40225 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MGLL Q99685 1/20 0.39
ADORA3 P0DMS8 1/20 0.37
EP300 Q09472 1/20 0.34
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP19A1 P11511 1/20 0.32
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10336238 0.87 F2 (0.42) F2ELANECTSGCTRCLMNA
SCHEMBL9334188 0.85 F2 (0.46) F2ELANECTSGCTRCLMNA
SCHEMBL14490041 0.80 F2 (0.43) F2ELANECTSGCTRCLMNA
SCHEMBL27601313 0.79 F2 (0.35) F2ELANECTSGCTRC
SCHEMBL1426468 0.78 ELANE (0.48) F2ELANECTSGCTRCLMNA
SCHEMBL12927818 0.74 F2 (1.00) F2ELANECTSGCTRCLMNA
SCHEMBL19103223 0.74 F2 (0.35) F2ELANECTSGCTRCLMNA
SCHEMBL11086325 0.73 TP53 (0.45) F2ELANECTSGCTRC
SCHEMBL1426485 0.73 LMNA (0.41) F2ELANECTSGCTRCLMNA
SCHEMBL15784520 0.72 F2 (0.41) F2ELANECTSGCTRCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746489-A1 PHOTOLABILE BARBITURATE COMPOUNDS 3M Innovative Properties Company (US) 2020-12-09 EP claimed
CN-111630072-A Photolabile barbiturate compound 3M创新有限公司 2020-09-04 CN claimed
WO-2019152187-A1 PHOTOLABILE BARBITURATE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-08 WO claimed
US-8853297-B2 Method and means for infiltrating enamel lesions CHARITE UNIVERSITATSMEDIZIN BERLIN (DE) 2014-10-07 US claimed
US-20090304622-A1 METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) 2009-12-10 US claimed
EP-2023884-A1 METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS Ernst Mühlbauer GmbH & Co.KG (DE) 2009-02-18 EP claimed
WO-2007131725-A1 METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS CHARITE-UNIVERSITÄTSMEDIZIN BERLIN (DE) 2007-11-22 WO claimed
CN-116635452-B Free radically polymerizable crosslinking agent, curable composition, and adhesive therefrom 3M INNOVATIVE PROPERTIES CO. (US) 2026-05-26 CN disclosed
US-12600885-B2 Composition including monomer with a carboxylic acid group, monomer with a hydroxyl group, an alkyl monomer, and crosslinker and related article and method 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-14 US disclosed
US-12497476-B2 Antibacterial polymer particles, composition, and article GC CORPORATION (JP) 2025-12-16 US disclosed
EP-4652982-A1 DENTAL RESTORATION MATERIAL COMPOSITION GC R&D Corporation (JP) 2025-11-26 EP disclosed
US-12398301-B2 Adhesives comprising cyclic imide addition-fragmentation and adhesion agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-08-26 US disclosed
US-12378340-B2 Crosslinkers and curable compositions including the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-08-05 US disclosed
US-6852775-B1 Polymerizable dental compositions 3M ESPE AG (DE) 2005-02-08 US disclosed
US-20040254261-A1 Dental composition GC CORPORATION (JP) 2004-12-16 US disclosed
EP-1462079-A1 Dental composition GC Corporation (JP) 2004-09-29 EP disclosed
US-20030158288-A1 Two-component dental materials having a low setting temperature 3M DEUTSCHLAND GMBH (DE) 2003-08-21 US disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
US-6174935-B1 Dental adhesive kit GC CORPORATION (JP) 2001-01-16 US disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497476-B2 Antibacterial polymer particles, composition, and article PCNA, PARG, PUF60 F2 1126/4885ELANE 1327/4885CTSG 955/4885
US-12600885-B2 Composition including monomer with a carboxylic acid group, monomer with a hydroxyl group, an alkyl monomer, and crosslinker and related article and method RAD51, HACL2, COL2A1 F2 655/4885ELANE 732/4885CTSG 4524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.