Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529435 | 0.86 | CYP11B1 (0.49) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL28532686 | 0.83 | HDAC1 (0.48) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL12827256 | 0.80 | CYP11B1 (0.55) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL14382237 | 0.77 | HDAC1 (0.53) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL24784588 | 0.73 | HDAC1 (0.55) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL4652514 | 0.73 | ALOX15 (0.53) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL5542313 | 0.73 | ALOX15 (0.53) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL9863750 | 0.73 | ALOX15 (0.53) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL4278243 | 0.73 | ALOX15 (0.53) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 | |
| SCHEMBL14367889 | 0.72 | CYP11B1 (0.51) | CYP11B1CYP11B2HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538058-B | Preparation method of oxazole-containing cyclic sulfone compound | 温州大学新材料与产业技术研究院 | 2022-05-27 | — | — | CN | disclosed |
| CN-112538058-A | Preparation method of oxazole-containing cyclic sulfone compound | 温州大学新材料与产业技术研究院 | 2021-03-23 | — | — | CN | disclosed |