Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012153 | 1.00 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL10011094 | 1.00 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL2851282 | 1.00 | — | — | |
| SCHEMBL11328673 | 0.97 | CES2 (0.35) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL3367972 | 0.97 | CES2 (0.35) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL3347229 | 0.97 | CES2 (0.35) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL7632244 | 0.97 | CES2 (0.35) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL14993205 | 0.97 | CES2 (0.35) | CES2CES1EPHX1NPC1RAB9A | |
| SCHEMBL10012897 | 0.97 | — | — | |
| SCHEMBL9993640 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853297-B2 | Method and means for infiltrating enamel lesions | CHARITE UNIVERSITATSMEDIZIN BERLIN (DE) | 2014-10-07 | — | — | US | claimed |
| US-20090304622-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) | 2009-12-10 | — | — | US | claimed |
| CN-101495081-A | Methods and tools for infiltrating enamel lesions | CHARITE UNIVERSITAETSMEDIZIN (DE) | 2009-07-29 | — | — | CN | claimed |
| EP-2023884-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | Ernst Mühlbauer GmbH & Co.KG (DE) | 2009-02-18 | — | — | EP | claimed |
| WO-2007131725-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2007-11-22 | — | — | WO | claimed |
| US-20250213436-A1 | POLYMERIZATION ACCELERATOR, POLYMERIZATION INITIATOR, CURABLE COMPOSITION PREPARATION KIT, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL | MITSUI CHEMICALS, INC. (JP) | 2025-07-03 | — | — | US | disclosed |
| US-12221524-B2 | Polymerization initiator, curable composition, dental material, and preparation kit for curable composition | MITSUI CHEMICALS, INC. (JP) | 2025-02-11 | — | — | US | disclosed |
| EP-4501974-A1 | POLYMERIZATION ACCELERATOR, POLYMERIZATION INITIATOR, KIT FOR PREPARING CURABLE COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT AND DENTAL MATERIAL | Mitsui Chemicals, Inc. (JP) | 2025-02-05 | — | — | EP | disclosed |
| EP-3666247-B1 | DIVIDED CURABLE COMPOSITION | MITSUI CHEMICALS INC (JP) | 2024-12-18 | — | — | EP | disclosed |
| EP-3835329-B1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | MITSUI CHEMICALS INC (JP) | 2024-05-01 | — | — | EP | disclosed |
| US-11844847-B2 | Sulfur-containing polymerizable monomer and use thereof | SUN MEDICAL CO., LTD. (JP) | 2023-12-19 | — | — | US | disclosed |
| CN-112513016-B | Sulfur-containing polymerizable monomer and use thereof | 尚美德齿科材料有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-2156817-A1 | REACTION-SETTING ADHESIVE COMPOSITION, AND ADHESIVE MATERIAL KIT FOR DENTAL APPLICATIONS | SUN MEDICAL CO., LTD. (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-20090304622-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) | 2009-12-10 | — | — | US | disclosed |
| CN-101495081-A | Methods and tools for infiltrating enamel lesions | CHARITE UNIVERSITAETSMEDIZIN (DE) | 2009-07-29 | — | — | CN | disclosed |
| EP-2023884-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | Ernst Mühlbauer GmbH & Co.KG (DE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007131725-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2007-11-22 | — | — | WO | disclosed |
| EP-0923924-B1 | Dental adhesive kit | SUN MEDICAL CO LTD (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-6288138-B1 | Dental adhesive kit | SUN MEDICAL CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0923924-A2 | Dental adhesive kit | SUN MEDICAL CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213436-A1 | POLYMERIZATION ACCELERATOR, POLYMERIZATION INITIATOR, CURABLE COMPOSITION PREPARATION KIT, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL | DNMT3L, CDK9, CDK6 | CES2 2336/4885CES1 3276/4885EPHX1 2357/4885 |
| US-11844847-B2 | Sulfur-containing polymerizable monomer and use thereof | MGMT, SETDB1, ASH2L | CES2 4247/4885CES1 4243/4885EPHX1 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.