Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846636 | 0.89 | ALDH1A1 (0.78) | ALDH1A1TSHRGAACYP3A4CYP1A2 | |
| SCHEMBL4208734 | 0.88 | ALDH1A1 (0.62) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL7355639 | 0.87 | TRPV1 (0.76) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL3721209 | 0.86 | TRPV1 (0.69) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL14564764 | 0.86 | TRPV1 (0.69) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL12635836 | 0.82 | HPGD (0.63) | ALDH1A1TSHRGAAALOX15KDM4E | |
| SCHEMBL28208051 | 0.81 | TRPV1 (0.63) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL7370094 | 0.80 | TRPV1 (0.61) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL5070307 | 0.80 | TRPV1 (0.61) | TRPV1ALDH1A1TSHRGAACYP3A4 | |
| SCHEMBL30646461 | 0.80 | ERCC1 (0.69) | TRPV1TSHRGAACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | claimed |
| EP-1915063-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-04-30 | — | — | EP | claimed |
| WO-2007013811-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-02-01 | — | — | WO | claimed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| EP-1915063-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| EP-1915063-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007013811-A3 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INT SERV BV (NL) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007013811-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-02-01 | — | — | WO | disclosed |
| WO-2007013811-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-02-01 | — | — | WO | disclosed |