SCHEMBL5070307

SCHEMBL5070307

COc1ccc(CNC(=O)c2c(O)cc(O)cc2O)cc1O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.61
CYP19A1 P11511 1/20 0.61
GAA P10253 3/20 0.54
TSHR P16473 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP3A4 P08684 1/20 0.54
ALOX15 P16050 1/20 0.54
RAB9A P51151 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
ALDH1A1 P00352 1/20 0.52
FAAH O00519 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 1/20 0.48
NR1H4 Q96RI1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899108 0.89 HPGD (0.56) TRPV1GAATSHRCYP3A4ALOX15
SCHEMBL30358380 0.89 HPGD (0.56) TRPV1GAATSHRCYP3A4ALOX15
SCHEMBL5065588 0.84 TRPV1 (0.59) TRPV1CYP19A1GAATSHRKDM4E
SCHEMBL16135569 0.83 LMNA (0.58) TRPV1GAATSHRKDM4ECYP3A4
SCHEMBL14564764 0.81 TRPV1 (0.69) TRPV1GAATSHRKDM4ECYP3A4
SCHEMBL3721209 0.81 TRPV1 (0.69) TRPV1GAATSHRKDM4ECYP3A4
SCHEMBL30646461 0.81 ERCC1 (0.69) TRPV1GAATSHRKDM4ECYP3A4
SCHEMBL2853305 0.80 TRPV1 (0.68) TRPV1GAATSHRKDM4ECYP3A4
SCHEMBL9416663 0.80 NR1H4 (0.64) TRPV1GAAMEN1KMT2AALDH1A1
SCHEMBL28208051 0.79 TRPV1 (0.63) TRPV1GAATSHRKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste SYMRISE GMBH & CO. KG (DE) 2008-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste TAS1R1, TAS2R1, TAS1R2 TRPV1 142/4885CYP19A1 3579/4885GAA 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.