Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138449 | 0.86 | GAA (0.68) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL28745588 | 0.86 | GAA (0.50) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL136681 | 0.85 | HDAC1 (0.60) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL1462899 | 0.85 | HDAC1 (0.57) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL2734577 | 0.85 | ABL1 (0.59) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL5421112 | 0.84 | HDAC1 (0.44) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL29354607 | 0.84 | LMNA (0.61) | ALDH1A1GAALMNAKDM4ETDP1 | |
| SCHEMBL187562 | 0.84 | LMNA (0.61) | ALDH1A1GAALMNAKDM4ETDP1 | |
| SCHEMBL7848228 | 0.83 | KDM4E (0.56) | HDAC1HDAC6ALDH1A1ABL1RIN1 | |
| SCHEMBL16930166 | 0.83 | HDAC1 (0.56) | HDAC1HDAC6ALDH1A1ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102260156-A | Method for preparing medicinal intermediate of p-methoxypropiophenone | — | 2011-11-30 | — | — | CN | disclosed |
| US-7645903-B2 | immunoglobulins; affinity chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2010-01-12 | — | — | US | disclosed |
| US-20090138208-A1 | IMMUNOGLOBULIN G BINDING POCKET | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2009-05-28 | — | — | US | disclosed |
| US-20060014735-A1 | Use of urea variants as affinity ligands | CYTIVA BIOPROCESS R&D AB (SE) | 2006-01-19 | — | — | US | disclosed |
| WO-2004039843-A1 | IMMUNOGLOBULIN G BINDING POCKET | AMERSHAM BIOSCIENCES AB (SE) | 2004-05-13 | — | — | WO | disclosed |
| WO-2004039765-A1 | USE OF UREA VARIANTS AS AFFINITY LIGANDS | AMERSHAM BIOSCIENCES AB (SE) | 2004-05-13 | — | — | WO | disclosed |
| US-6093851-A | N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0735018-B1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL CO (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5877191-A | ANTIINFLAMMATORY AGENT; ANALGESICS; ANTIHISTAMINES; EMESIS | MERCK & CO., INC. (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1998017660-A1 | PHENYL SPIROETHERCYCLOALKYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-04-30 | — | — | WO | disclosed |
| US-5739401-A | N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0735018-A1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014735-A1 | Use of urea variants as affinity ligands | IGLV6-57, FCGR2A, FCGR3B | HDAC1 4024/4885HDAC6 2606/4885ALDH1A1 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.