Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24663014 | 1.00 | SIRT6 (0.49) | SIRT6MAPTCYP3A4BLMPMP22 | |
| SCHEMBL24662997 | 1.00 | SIRT6 (0.49) | SIRT6MAPTCYP3A4BLMPMP22 | |
| SCHEMBL28519341 | 0.89 | SIRT6 (0.50) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28533378 | 0.89 | SIRT6 (0.50) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28519340 | 0.89 | SIRT6 (0.50) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24663046 | 0.85 | SIRT6 (0.47) | SIRT6MAPTCYP3A4BLMPMP22 | |
| SCHEMBL23316344 | 0.85 | SIRT6 (0.47) | SIRT6MAPTCYP3A4BLMPMP22 | |
| SCHEMBL23316349 | 0.85 | SIRT6 (0.47) | SIRT6MAPTCYP3A4BLMPMP22 | |
| SCHEMBL24662923 | 0.85 | THRB (0.42) | SIRT6MAPTCYP3A4BLMPMP22 | |
| SCHEMBL24663012 | 0.85 | THRB (0.42) | SIRT6MAPTCYP3A4BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-112469707-A | Prophylactic or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2021-03-09 | — | — | CN | disclosed |