Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533487 | 1.00 | PARP10 (0.35) | PARP10PARP15PARP2P2RX3P2RX2 | |
| SCHEMBL29279746 | 0.84 | CHRNB2 (0.48) | PARP10PARP15PARP2GPR119CHRNA7 | |
| SCHEMBL21492131 | 0.79 | CHRNB2 (0.35) | P2RX3P2RX2 | |
| SCHEMBL21492093 | 0.79 | CHRNB2 (0.35) | P2RX3P2RX2 | |
| SCHEMBL21492249 | 0.76 | P2RX3 (0.38) | P2RX3P2RX2FFAR1 | |
| SCHEMBL21492250 | 0.76 | P2RX3 (0.38) | P2RX3P2RX2FFAR1 | |
| SCHEMBL29042321 | 0.76 | FFAR1 (0.54) | FFAR1 | |
| SCHEMBL21492176 | 0.73 | P2RX3 (0.35) | P2RX3P2RX2FFAR1 | |
| SCHEMBL21492177 | 0.73 | P2RX3 (0.35) | P2RX3P2RX2FFAR1 | |
| SCHEMBL21503407 | 0.72 | KMT2A (0.39) | P2RX3P2RX2GPR119ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |