Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390615 | 0.84 | HRH3 (0.40) | ATMHRH3AOC3PARP1L3MBTL3 | |
| SCHEMBL21873698 | 0.81 | ATM (0.47) | ATMOPRM1DPP4DPP8DPP9 | |
| SCHEMBL4975174 | 0.78 | ATM (0.41) | ATML3MBTL1KDM4E | |
| SCHEMBL28649982 | 0.74 | DPP4 (0.44) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28370719 | 0.71 | ATM (0.41) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28946887 | 0.71 | DPP4 (0.53) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28366249 | 0.71 | ATM (0.41) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28663265 | 0.71 | DPP4 (0.53) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28851434 | 0.71 | L3MBTL1 (0.39) | ATMDPP4HRH3ALDH1A1AOC3 | |
| SCHEMBL28851429 | 0.71 | L3MBTL1 (0.39) | ATMDPP4HRH3ALDH1A1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |