Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537348 | 0.77 | MAPK1 (0.44) | MAPTKDM4ELMNAPOLBCYP2C9 | |
| SCHEMBL28908810 | 0.74 | VKORC1 (0.50) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL14300755 | 0.72 | APP (0.52) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL28530799 | 0.71 | NQO1 (0.48) | KDM4EMAPK1NQO1 | |
| SCHEMBL28539636 | 0.70 | TOP2A (0.39) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL28534246 | 0.70 | NQO1 (0.47) | MAPTALDH1A1KDM4ELMNACYP2C9 | |
| SCHEMBL28534244 | 0.70 | TOP2A (0.39) | ALDH1A1HPGDKDM4ELMNATP53 | |
| SCHEMBL28537368 | 0.70 | KDM4E (0.45) | MAPTALDH1A1KDM4ELMNATP53 | |
| SCHEMBL9578548 | 0.68 | MAPT (0.43) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL28536694 | 0.68 | CYP1A2 (0.42) | ALDH1A1KDM4EMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112517060-B | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112517060-A | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2021-03-19 | — | — | CN | disclosed |