Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523379 | 0.89 | LMNA (0.60) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL28907541 | 0.84 | LMNA (0.61) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL28535985 | 0.84 | LMNA (0.61) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL28518116 | 0.83 | LMNA (0.60) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL28535984 | 0.75 | MEN1 (0.58) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL881339 | 0.75 | LMNA (0.84) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL1395039 | 0.73 | LMNA (1.00) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL1392634 | 0.72 | LMNA (0.92) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL8236728 | 0.72 | LMNA (0.74) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL4884971 | 0.71 | LMNA (0.90) | LMNAATG4BMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | disclosed |