Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.90 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | CASP6 | P55212 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1392634 | 0.99 | LMNA (0.92) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL1395039 | 0.95 | LMNA (1.00) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL5836289 | 0.89 | LMNA (0.85) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL881339 | 0.89 | LMNA (0.84) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL13681844 | 0.88 | LMNA (0.78) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL8236728 | 0.88 | LMNA (0.74) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL10253068 | 0.85 | LMNA (0.77) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL375490 | 0.84 | LMNA (0.76) | LMNAATG4BMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL28533675 | 0.83 | LMNA (0.74) | LMNAATG4BMEN1KMT2ARAB9A | |
| SCHEMBL14906480 | 0.83 | LMNA (0.74) | LMNAATG4BMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420828-B1 | LIPOPHILIC DRUG COMPOSITIONS | SUNG MICHAEL T (US) | 2012-09-26 | — | — | EP | claimed |
| US-7390506-B2 | Lipophilic drug compositions | PHARMALIPOCORE, INC. | 2008-06-24 | — | — | US | claimed |
| US-20060147525-A1 | Lipophilic drug compositions | PHARMALIPOCORE, INC. | 2006-07-06 | — | — | US | claimed |
| EP-1420828-B1 | LIPOPHILIC DRUG COMPOSITIONS | SUNG MICHAEL T (US) | 2012-09-26 | — | — | EP | disclosed |
| US-7390506-B2 | Lipophilic drug compositions | PHARMALIPOCORE, INC. | 2008-06-24 | — | — | US | disclosed |
| US-7125568-B2 | Lipophilic drug compositions | SUNG, ROSEMARY | 2006-10-24 | — | — | US | disclosed |
| US-20060147525-A1 | Lipophilic drug compositions | PHARMALIPOCORE, INC. | 2006-07-06 | — | — | US | disclosed |
| EP-1420828-A2 | LIPOPHILIC DRUG COMPOSITIONS | Sung, Michael T. (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20030108596-A1 | Lipophilic drug compositions | SUNG, ROSEMARY | 2003-06-12 | — | — | US | disclosed |
| WO-2003018064-A2 | LIPOPHILIC DRUG COMPOSITIONS | SUNG MICHAEL T (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108596-A1 | Lipophilic drug compositions | LIPA, LIPC, PNLIP | LMNA 1277/4885ATG4B 926/4885MEN1 3372/4885 |
| US-20060147525-A1 | Lipophilic drug compositions | LIPA, LIPC, PNLIP | LMNA 1277/4885ATG4B 926/4885MEN1 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.