Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.35 |
| ▸ | F2R | P25116 | 4/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540107 | 1.00 | SRD5A2 (0.39) | SRD5A2PTGER4F2RLTA4HPSEN1 | |
| SCHEMBL23631891 | 1.00 | SRD5A2 (0.39) | SRD5A2PTGER4F2RLTA4HPSEN1 | |
| SCHEMBL28537484 | 0.91 | SRD5A2 (0.38) | SRD5A2PTGER4LTA4HPSEN1PSEN2 | |
| SCHEMBL21616610 | 0.91 | SRD5A2 (0.38) | SRD5A2PTGER4F2RLTA4HPSEN1 | |
| SCHEMBL28529305 | 0.91 | SRD5A2 (0.38) | SRD5A2PTGER4LTA4HPSEN1PSEN2 | |
| SCHEMBL21619810 | 0.91 | MAOB (0.38) | F2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28542902 | 0.89 | KDM4E (0.42) | F2RCCR2KCNH2 | |
| SCHEMBL23632260 | 0.89 | KDM4E (0.42) | F2RCCR2KCNH2 | |
| SCHEMBL28910602 | 0.88 | FPR1 (0.41) | SRD5A2PTGER4F2RLTA4HADRA2A | |
| SCHEMBL28532591 | 0.87 | SRD5A2 (0.36) | SRD5A2PTGER4F2RLTA4HPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |