SCHEMBL28533699

SCHEMBL28533699

O=C(CI)CCCNC(=O)NCc1ccc(CO)c([N+](=O)[O-])c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.42
CXCR4 P61073 1/20 0.38
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA4 P22748 3/20 0.37
CA5A P35218 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
CA14 Q9ULX7 3/20 0.37
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
EPHX2 P34913 1/20 0.35
HPGD P15428 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C19 P33261 2/20 0.35
LMNA P02545 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28539403 0.86 NPC1 (0.41) NPC1RAB9AMEN1KMT2AEPHX2
SCHEMBL28530396 0.86 PTPN1 (0.50) PTPN1CXCR4NPC1RAB9AMEN1
SCHEMBL28539545 0.84 CXCR4 (0.47) CXCR4MEN1KMT2AHDAC3HDAC4
Hydrochloric Acid SCHEMBL28536803 0.82 PTPN1 (0.42) PTPN1CXCR4CA12CA1CA2
SCHEMBL28536922 0.80 NPC1 (0.46) PTPN1CXCR4NPC1RAB9AMEN1
SCHEMBL28541709 0.78 ALDH1A1 (0.47) MEN1KMT2AHPGDLMNASMN1; SMN2
SCHEMBL28551730 0.78 OPRM1 (0.46) PTPN1CXCR4NPC1RAB9AMEN1
SCHEMBL29450344 0.74 CYP2C19 (0.45) PTPN1CXCR4NPC1RAB9AMEN1
SCHEMBL28538471 0.73 CXCR4 (0.48) CXCR4NPC1RAB9ACYP1A2CYP3A4
SCHEMBL28535807 0.72 NPC1 (0.46) PTPN1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574089-B Photo-induced multifunctional crosslinking agent, preparation method and application thereof 中国科学院上海药物研究所 2023-09-05 CN disclosed
CN-112574089-A Photoinduced multifunctional cross-linking agent, and preparation method and application thereof 中国科学院上海药物研究所 2021-03-30 CN disclosed