Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540869 | 1.00 | RBP4 (0.39) | RBP4ACACBHDAC3HDAC4HDAC1 | |
| SCHEMBL28910594 | 0.91 | ACACB (0.38) | RBP4ACACBHDAC3HDAC4HDAC1 | |
| SCHEMBL21619926 | 0.86 | ACACB (0.36) | ACACBHRH3PSEN1PSEN2APH1B | |
| SCHEMBL21616679 | 0.86 | RBP4 (0.43) | RBP4ACACBHDAC3HDAC4HDAC1 | |
| SCHEMBL28526800 | 0.86 | RBP4 (0.39) | RBP4ACACBHDAC3HDAC4HDAC1 | |
| SCHEMBL28537090 | 0.86 | PTGIR (0.40) | RBP4ACACBHDAC3HDAC4HDAC1 | |
| SCHEMBL23631891 | 0.85 | SRD5A2 (0.39) | F2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28540107 | 0.85 | SRD5A2 (0.39) | F2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28533682 | 0.85 | SRD5A2 (0.39) | F2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23632735 | 0.85 | ACACB (0.38) | RBP4ACACBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |