SCHEMBL28533875

SCHEMBL28533875

CCC(C)(C(=O)O)c1ccc(CCCl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 2/20 0.41
ESRRG P62508 3/20 0.38
ALDH1A1 P00352 3/20 0.37
PPARA Q07869 2/20 0.37
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
NR1H4 Q96RI1 2/20 0.35
EPHX2 P34913 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
AKT1 P31749 1/20 0.35
ESRRB O95718 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993574 0.81 HRH3 (0.47) SLC13A5ESRRGALDH1A1PPARAKMT2A
SCHEMBL1626113 0.79 MIF (0.48) PPARAMEN1CYP1A2KMT2ANPC1
SCHEMBL20556837 0.79 MIF (0.48) PPARAMEN1CYP1A2KMT2ANPC1
SCHEMBL28410527 0.78 FFAR1 (0.55) ALDH1A1RXRARXRBRXRGNR1H4
SCHEMBL8494650 0.78 SMN1; SMN2 (0.47) SLC13A5ESRRGALDH1A1MEN1CYP1A2
Hydrochloric Acid SCHEMBL8663111 0.77 MIF (0.47) PPARAMEN1CYP1A2KMT2ANPC1
SCHEMBL28890691 0.77 FFAR1 (0.54) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL28410584 0.77 FFAR1 (0.50) SLC13A5ALDH1A1RXRARXRBRXRG
SCHEMBL28915433 0.77 NPC1 (0.46) ALDH1A1MEN1CYP1A2KMT2AHPGD
SCHEMBL8148677 0.77 ESR1 (0.52) ESRRGALDH1A1MEN1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112469709-A Preparation method of bilastine and intermediate thereof 费斯制药股份有限公司 2021-03-09 CN disclosed