Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439832 | 0.85 | HRH3 (0.49) | HRH3SLC13A5ESRRGPPARAALDH1A1 | |
| SCHEMBL10975329 | 0.85 | CA1 (0.44) | HRH3SLC13A5PPARALTB4RLTB4R2 | |
| SCHEMBL992215 | 0.83 | PPARA (0.57) | HRH3SLC13A5ESRRGPPARARXRA | |
| SCHEMBL28340064 | 0.81 | PPARA (0.56) | HRH3SLC13A5ESRRGPPARARXRA | |
| SCHEMBL21629639 | 0.81 | BRS3 (0.53) | ESRRGALDH1A1NR1H4EPHX2NPC1 | |
| SCHEMBL28533875 | 0.81 | SLC13A5 (0.41) | SLC13A5ESRRGPPARAALDH1A1RXRA | |
| Hydrochloric Acid SCHEMBL11112027 | 0.80 | TAAR1 (0.48) | HRH3SLC13A5ESRRGALDH1A1MAPT | |
| SCHEMBL8587467 | 0.80 | ALDH1A1 (0.58) | HRH3ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19941943 | 0.80 | ESRRG (0.40) | SLC13A5ESRRGPPARAALDH1A1RXRA | |
| SCHEMBL3669281 | 0.80 | TDP1 (0.41) | HRH3SLC13A5ESRRGLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018042305-A1 | IMPROVED PROCESSES FOR PREPARATION OF BILASTINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2018-03-08 | — | — | WO | claimed |
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2025-04-24 | — | — | US | disclosed |
| WO-2023037184-A2 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2023-03-16 | — | — | WO | disclosed |
| CN-112521267-A | Preparation method of bilastine key intermediate | 北京万全德众医药生物技术有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112521267-A | Preparation method of bilastine key intermediate | 北京万全德众医药生物技术有限公司 | 2021-03-19 | — | — | CN | disclosed |
| WO-2018042305-A1 | IMPROVED PROCESSES FOR PREPARATION OF BILASTINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |
| WO-2018042305-A1 | IMPROVED PROCESSES FOR PREPARATION OF BILASTINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |
| CN-107365298-A | A kind of preparation method of the benzyl propionate derivant of 2 methyl 2 ' | 罗欣生物科技（上海）有限公司 | 2017-11-21 | — | — | CN | disclosed |
| US-8633223-B2 | Process for preparation of 2-methyl-2′-phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2014-01-21 | — | — | US | disclosed |
| US-8487106-B2 | Process for preparation of 2-methyl-2′-phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2013-07-16 | — | — | US | disclosed |
| US-20130116439-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2013-05-09 | — | — | US | disclosed |
| US-20130116466-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2013-05-09 | — | — | US | disclosed |
| US-8367704-B2 | Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2013-02-05 | — | — | US | disclosed |
| US-20110009636-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KP) | 2011-01-13 | — | — | US | disclosed |
| EP-2240464-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | Yuhan Corporation (KR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009102155-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009636-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH4, HCAR2, HRH1 | HRH3 7/4885SLC13A5 526/4885ESRRG 4785/4885 |
| US-20130116439-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH2, HRH4, HNMT | HRH3 5/4885SLC13A5 1247/4885ESRRG 4802/4885 |
| US-20130116466-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH1, HRH2, HRH4 | HRH3 6/4885SLC13A5 667/4885ESRRG 4732/4885 |
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | CYP4B1, CYP3A4, CYP7A1 | HRH3 22/4885SLC13A5 2208/4885ESRRG 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.