Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487532 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL6898512 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL4594030 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL1539071 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL11533806 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL31589829 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL4661794 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| Water SCHEMBL17698009 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| Hydrochloric Acid SCHEMBL3047334 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL8849475 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187644-B2 | Continuous processing of asphalt formulations | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140275337-A1 | CONTINUOUS PROCESSING OF ASPHALT FORMULATIONS | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-7781610-B2 | Heterogeneous organotin catalysts | CHEMTURA CORPORATION (US) | 2010-08-24 | — | — | US | disclosed |
| US-7772417-B2 | Heterogeneous organotin catalysts | CHEMTURA CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20100174106-A1 | HETEROGENEOUS ORGANOTIN CATALYSTS | CHEMTURA CORPORATION (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100152477-A1 | HETEROGENEOUS ORGANOTIN CATALYSTS | CHEMTURA CORPORATION (US) | 2010-06-17 | — | — | US | disclosed |
| US-7687581-B2 | Heterogeneous organotin catalysts | CHEMTURA CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| EP-1389620-B1 | Process for the preparation of mono- and dialkyltin halogen compounds and use thereof | CHEMTURA ORGANOMETALLICS GMBH (DE) | 2008-12-31 | — | — | EP | disclosed |
| EP-1598381-B1 | Heterogeneous organotin catalysts | CHEMTURA ORGANOMETALLICS GMBH (DE) | 2006-10-18 | — | — | EP | disclosed |
| CN-1714935-A | Heterogeneous organotin catalysts | CROMPTON GMBH (DE) | 2006-01-04 | — | — | CN | disclosed |
| US-6846944-B2 | Process for preparing monoalkyltin halides and dialkyltin halides and their use | CROMPTON GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040133022-A1 | Process for preparing monoalkyltin halides and dialkyltin halides and their use | PMC VLISSINGEN NETHERLANDS, B.V. (NL) | 2004-07-08 | — | — | US | disclosed |
| EP-1389620-A1 | Process for the preparation of mono- and dialkyltin halogen compounds and use thereof | Crompton GmbH (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-4988750-A | Halogenated polymer and didodecyltin bisthioglycolic acid ester and dodecyltin tristhioglycolic acid ester | SCHERING AG (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0011456-B1 | ORGANOTIN COMPOUNDS AND RESINS OR POLYMERS STABILIZED THEREWITH | M & T CHEMICALS, INC. (US) | 1983-09-07 | — | — | EP | disclosed |
| US-4254017-A | HEAT STABILIZER FOR POLYVINYL CHLORIDE | M&T CHEMICALS INC. (US) | 1981-03-03 | — | — | US | disclosed |
| EP-0011456-A1 | Organotin compounds and resins or polymers stabilized therewith | M & T CHEMICALS, INC. (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4148814-A | Process for preparing monohydrocarbyltin trihalides | PENNWALT CORPORATION (US) | 1979-04-10 | — | — | US | disclosed |
| US-4093636-A | IN PRESENCE OF ORGANIC HYDROPEROXIDES AND A TIN CATALYST | RHONE - POULENC INDUSTRIES (FR) | 1978-06-06 | — | — | US | disclosed |
| US-4010141-A | Anti-fouling composition for use in water comprising a polymer and an organo tin compound | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174106-A1 | HETEROGENEOUS ORGANOTIN CATALYSTS | ATXN2L, CDYL, ZYX | TSHR 1583/4885THRB 2896/4885ALDH1A1 3536/4885 |
| US-20100152477-A1 | HETEROGENEOUS ORGANOTIN CATALYSTS | ATXN2L, CDYL, ZYX | TSHR 1583/4885THRB 2896/4885ALDH1A1 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.