SCHEMBL6898512

SCHEMBL6898512

CCCCCCCCCCCCCCCCCCCC[Sn](Cl)(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853403 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL1487532 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL4594030 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL1539071 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11533806 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL31589829 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL4661794 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
Water SCHEMBL17698009 0.97 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
Hydrochloric Acid SCHEMBL3047334 0.97 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8849475 0.97 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866090-B1 Improved PVC foam compositions MORTON INT INC (US) 2004-04-21 EP disclosed
EP-0850987-B1 Improved PVC foam compositions MORTON INT INC (US) 2002-03-27 EP disclosed
US-5866625-A DENSITY REDUCED BY THE USE OF AN ORGANOTIN HALIDE IN COMBINATION WITH A MERCAPTOCARBOXYLIC ACID ESTER OR A SULFIDE OF SUCH ESTER MORTON INTERNATIONAL, INC. (US) 1999-02-02 US disclosed
EP-0866090-A1 Improved PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-09-23 EP disclosed
US-5786399-A PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-28 US disclosed
US-5783613-A ORGANOTIN COMPOUNDS AS ACTIVATOR FOR BLOWING AGENT MORTON INTERNATIONAL, INC. (US) 1998-07-21 US disclosed
EP-0850987-A1 Improved PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-01 EP disclosed
US-5753719-A ACTIVATOR FOR BLOWING AGENTS MORTON INTERNATIONAL, INC. (US) 1998-05-19 US disclosed
US-5726213-A FOAMING VINYL CHLORIDE POLYMER BY HEATING MIXTURE OF POLYMER, BLOWING AGENT, STABILIZER INCLUDING ORGANOTIN MERCAPTIDE OF MERCAPTOALKYL CARBOXYLATE OR SULFIDE THEREOF, OPTIONAL ORGANOTIN SALT MORTON INTERNATIONAL, INC. (US) 1998-03-10 US disclosed
US-5710188-A HEATING A MIXTURE OF POLYVINYL CHLORIDE, A BLOWING AGENT, AN ORGANOTIN HALIDE AND A STABILIZER TO FOAM POLYMER MORTON INTERNATIONAL, INC. (US) 1998-01-20 US disclosed
EP-0011456-B1 ORGANOTIN COMPOUNDS AND RESINS OR POLYMERS STABILIZED THEREWITH M & T CHEMICALS, INC. (US) 1983-09-07 EP disclosed
US-4254017-A HEAT STABILIZER FOR POLYVINYL CHLORIDE M&T CHEMICALS INC. (US) 1981-03-03 US disclosed
EP-0011456-A1 Organotin compounds and resins or polymers stabilized therewith M & T CHEMICALS, INC. (US) 1980-05-28 EP disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-4120845-A FOR VINYL OR VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1978-10-17 US disclosed
US-4062881-A POLYVINYL CHLORIDE CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-12-13 US disclosed