Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 6/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531272 | 0.86 | MAPT (0.47) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL28532114 | 0.86 | MAPT (0.47) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL28531699 | 0.86 | MAPT (0.47) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL6174518 | 0.81 | VKORC1 (0.55) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL28537368 | 0.78 | KDM4E (0.45) | MAPTMCL1ALDH1A1GAAMGAM | |
| SCHEMBL6174415 | 0.78 | CYP2C9 (0.58) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL7408954 | 0.76 | MAPT (0.53) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL6175188 | 0.76 | PPARG (0.52) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL6172211 | 0.75 | MAPT (0.47) | MAPTMCL1PTGESALDH1A1GAA | |
| SCHEMBL6173554 | 0.72 | MAPT (0.47) | MAPTMCL1PTGESALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112517060-B | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112517060-A | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2021-03-19 | — | — | CN | disclosed |