Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527643 | 0.92 | CALCRL (0.49) | CALCRL | |
| SCHEMBL28522965 | 0.89 | CALCRL (0.49) | CALCRLRIPK1 | |
| SCHEMBL20835829 | 0.87 | CALCRL (0.47) | CALCRLRIPK1 | |
| SCHEMBL28523772 | 0.85 | CALCRL (0.42) | CALCRLRIPK1 | |
| SCHEMBL21094099 | 0.85 | CALCRL (0.41) | CALCRL | |
| SCHEMBL28515703 | 0.83 | ABCB1 (0.43) | CALCRLRIPK1GPR119 | |
| SCHEMBL28527635 | 0.83 | CALCRL (0.50) | CALCRL | |
| SCHEMBL22441102 | 0.81 | CALCRL (0.49) | CALCRLRIPK1 | |
| SCHEMBL22451402 | 0.81 | CALCRL (0.49) | CALCRLRIPK1 | |
| SCHEMBL19803592 | 0.81 | CALCRL (0.49) | CALCRLRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |