Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 8/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835904 | 0.88 | RIPK1 (0.50) | CALCRLRIPK1 | |
| SCHEMBL28534302 | 0.85 | CALCRL (0.46) | CALCRLRIPK1 | |
| SCHEMBL20835753 | 0.84 | RIPK1 (0.43) | CALCRLRIPK1FFAR2 | |
| SCHEMBL20835577 | 0.82 | FFAR2 (0.51) | RIPK1CHRM2CHRM1CHRM3FFAR2 | |
| SCHEMBL28518933 | 0.82 | FFAR2 (0.41) | RIPK1CHRM2CHRM1CHRM3FFAR2 | |
| SCHEMBL28520937 | 0.80 | FFAR2 (0.40) | CALCRLRIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL28527643 | 0.79 | CALCRL (0.49) | CALCRL | |
| SCHEMBL20835781 | 0.79 | CALCRL (0.47) | CALCRLRIPK1DPP4 | |
| SCHEMBL20843549 | 0.79 | CALCRL (0.47) | CALCRLRIPK1DPP4 | |
| SCHEMBL20835783 | 0.79 | CALCRL (0.47) | CALCRLRIPK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |