Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87590 | 0.84 | — | — | |
| SCHEMBL29076624 | 0.76 | — | — | |
| SCHEMBL28908026 | 0.76 | — | — | |
| SCHEMBL28440637 | 0.74 | — | — | |
| SCHEMBL28919217 | 0.74 | — | — | |
| SCHEMBL28601820 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5372828 | 0.73 | THRB (0.31) | THRBBLMPMP22KMT2A | |
| SCHEMBL2139683 | 0.72 | — | — | |
| SCHEMBL1516652 | 0.72 | — | — | |
| SCHEMBL28900268 | 0.72 | LMNA (0.42) | TSHRHSD17B10TDP1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150030-A | Oxabicycloheptane prodrugs | 莱克斯特生物技术公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107708686-B | Oxabicycloheptane prodrugs | 莱克斯特生物技术公司 | 2021-02-19 | — | — | CN | disclosed |