Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616577 | 1.00 | PROKR1 (0.37) | PROKR1ACACBRBP4P2RY14SCN9A | |
| SCHEMBL21616583 | 1.00 | PROKR1 (0.37) | PROKR1ACACBRBP4P2RY14SCN9A | |
| SCHEMBL21616590 | 1.00 | PROKR1 (0.37) | PROKR1ACACBRBP4P2RY14SCN9A | |
| SCHEMBL28529263 | 0.92 | RBP4 (0.38) | PROKR1ACACBRBP4P2RY14HDAC3 | |
| SCHEMBL28526859 | 0.90 | MAOB (0.38) | PROKR1ACACB | |
| SCHEMBL28537468 | 0.90 | MAOB (0.38) | PROKR1ACACB | |
| SCHEMBL23632375 | 0.86 | P2RY14 (0.37) | PROKR1P2RY14ADRB3ADRA2CDRD1 | |
| SCHEMBL21616632 | 0.86 | P2RY14 (0.37) | PROKR1P2RY14ADRB3ADRA2CDRD1 | |
| SCHEMBL23631928 | 0.86 | P2RY14 (0.37) | PROKR1P2RY14ADRB3ADRA2CDRD1 | |
| SCHEMBL28616314 | 0.86 | P2RY14 (0.37) | PROKR1P2RY14ADRB3ADRA2CDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |