SCHEMBL28534683

SCHEMBL28534683

CS(=O)(=O)C1CCC(O)(COC(N)=O)C(O)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 19/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28511823 0.78 FUCA1 (0.31)
SCHEMBL28538887 0.78 ALOX15 (0.34) RORC
Hydrochloric Acid SCHEMBL21598070 0.78 FUCA1 (0.31)
Hydrochloric Acid SCHEMBL23189663 0.78 FUCA1 (0.31)
SCHEMBL28538886 0.78 ALOX15 (0.34) RORC
Hydrochloric Acid SCHEMBL23189773 0.78 FUCA1 (0.31)
SCHEMBL23189831 0.73 RORC (0.39) RORC
SCHEMBL23189651 0.73 RORC (0.39) RORC
SCHEMBL23189794 0.73 RORC (0.39) RORC
SCHEMBL21607302 0.73 RORC (0.40) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566901-A Phenyl-substituted pyrazoles as modulators of ROR γ t 詹森药业有限公司 2021-03-26 CN disclosed
CN-112334450-A Phenyl and pyridyl substituted imidazoles as modulators of ROR γ t 詹森药业有限公司 2021-02-05 CN disclosed
CN-112292373-A Pyridylpyrazoles as modulators of ROR γ t 詹森药业有限公司 2021-01-29 CN disclosed
CN-112292183-A 6-aminopyridin-3-yl-pyrazoles as modulators of ROR γ t 詹森药业有限公司 2021-01-29 CN disclosed