Pyridine

Pyridine

SCHEMBL28534733

c1ccc(-n2cccn2)cc1.c1ccncc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.57
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPK1 P28482 3/20 0.52
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
DRD3 P35462 1/20 0.50
HDAC4 P56524 1/20 0.44
NPC1 O15118 2/20 0.43
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA10 Q9GZZ6 1/20 0.41
CHRNA9 Q9UGM1 1/20 0.41
CHRM1 P11229 1/20 0.40
KAT6A Q92794 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27250 0.91 NOTUM (0.65) NOTUMALDH1A1KDM4EMAPK1DRD2
SCHEMBL6428811 0.89 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2
SCHEMBL28493417 0.89 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2
SCHEMBL514704 0.89 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2
SCHEMBL842039 0.89 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2
Hydrochloric Acid SCHEMBL15510676 0.89 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2
Iodide SCHEMBL336356 0.89 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2
Methylamine SCHEMBL27947262 0.85 NOTUM (0.59) NOTUMALDH1A1KDM4EMAPK1DRD2
Formaldehyde SCHEMBL27652263 0.85 NOTUM (0.59) NOTUMALDH1A1KDM4EMAPK1DRD2
SCHEMBL4473412 0.85 NOTUM (0.63) NOTUMALDH1A1KDM4EMAPK1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552350-A Organic electroluminescent material and device 环球展览公司 2021-03-26 CN disclosed