Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16827815 | 0.98 | NOTUM (0.61) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL4341894 | 0.87 | NOTUM (0.78) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| Pyridine SCHEMBL28534733 | 0.85 | NOTUM (0.57) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL27250 | 0.83 | NOTUM (0.65) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL16549641 | 0.82 | KDM4E (0.64) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL514704 | 0.81 | NOTUM (0.63) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL6428811 | 0.81 | NOTUM (0.63) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| Hydrochloric Acid SCHEMBL15510676 | 0.81 | NOTUM (0.63) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL842039 | 0.81 | NOTUM (0.63) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 | |
| SCHEMBL28493417 | 0.81 | NOTUM (0.63) | NOTUMKDM4EALDH1A1MAPK1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076088-A1 | LACTAMS FOR USE AS SARM1 INHIBITORS | GENENTECH, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025040546-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-02-27 | — | — | WO | disclosed |
| US-20240368173-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2024-11-07 | — | — | US | disclosed |
| US-20230271941-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-31 | — | — | US | disclosed |
| CN-116655699-A | Bivalent platinum complex white phosphorus light material and device application thereof | 南京佳诺霖光电科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| CN-103327972-A | Substituted benzamides and their uses | UNIV LELAND STANFORD JUNIOR | 2013-09-25 | — | — | CN | disclosed |
| WO-2012143144-A1 | PYRAZOLO [4, 3-D] PYRIMIDINES USEFUL AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| CN-102712625-A | Nitrogen-containing heteroaryl derivatives | HOFFMANN LA ROCHE | 2012-10-03 | — | — | CN | disclosed |
| CN-101765600-A | pyrazolopyrimidinone kinase inhibitor | GPC BIOTECH AG | 2010-06-30 | — | — | CN | disclosed |
| US-7491737-B2 | Heterarylpiperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20050250781-A1 | Heterarylpiperidine modulators of chemokine receptor activity | MERCK SHARP & DOHME CORP. | 2005-11-10 | — | — | US | disclosed |
| EP-1142890-A1 | AMINOPYRAZOLE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-0159011-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| US-4833242-A | ANTIBIOTICS, BACTERICIDES | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0159011-A2 | Cephalosporin derivatives, process for preparing them and pharmaceutical compositions containing them | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368173-A1 | TRICYCLIC GPR65 MODULATORS | GPR65, GPR3, NR1H2 | NOTUM 4311/4885KDM4E 3978/4885ALDH1A1 2926/4885 |
| US-20230271941-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | NOTUM 4501/4885KDM4E 3761/4885ALDH1A1 4654/4885 |
| US-20050250781-A1 | Heterarylpiperidine modulators of chemokine receptor activity | CCR1, CCR2, CCRL2 | NOTUM 3878/4885KDM4E 4493/4885ALDH1A1 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.