Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842039 | 1.00 | NOTUM (0.63) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| SCHEMBL27250 | 0.98 | NOTUM (0.65) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| SCHEMBL28493417 | 0.95 | NOTUM (0.63) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| Iodide SCHEMBL336356 | 0.95 | NOTUM (0.63) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| SCHEMBL6428811 | 0.95 | NOTUM (0.63) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL15510676 | 0.95 | NOTUM (0.63) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| Methylamine SCHEMBL27947262 | 0.91 | NOTUM (0.59) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| Formaldehyde SCHEMBL27652263 | 0.91 | NOTUM (0.59) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| Bicarbonate SCHEMBL10672835 | 0.89 | NOTUM (0.57) | NOTUMALDH1A1MAPK1KDM4EDRD2 | |
| Pyridine SCHEMBL28534733 | 0.89 | NOTUM (0.57) | NOTUMALDH1A1MAPK1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116667-B | Iridium complex constructed based on 8-hydroxyquinoline derivative and 1-phenylpyrazole iridium dimer as well as synthetic method and application thereof | 广西师范大学 | 2021-05-04 | — | — | CN | disclosed |
| CN-111116667-B | Iridium complex constructed based on 8-hydroxyquinoline derivative and 1-phenylpyrazole iridium dimer as well as synthetic method and application thereof | 广西师范大学 | 2021-05-04 | — | — | CN | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| CN-111116667-A | Iridium complex constructed based on 8-hydroxyquinoline derivative and 1-phenylpyrazole iridium dimer as well as synthetic method and application thereof | 广西师范大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-111116667-A | Iridium complex constructed based on 8-hydroxyquinoline derivative and 1-phenylpyrazole iridium dimer as well as synthetic method and application thereof | 广西师范大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-3109238-B1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | UNIV SOUTHERN CALIFORNIA (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2018-01-18 | — | — | US | disclosed |
| US-9583720-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-28 | — | — | US | disclosed |
| EP-3109238-A1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | University of Southern California (US) | 2016-12-28 | — | — | EP | disclosed |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | THOMPSON MARK E | 2008-07-24 | — | — | US | disclosed |
| CN-100387607-C | Phenyl-pyrazole complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2008-05-14 | — | — | CN | disclosed |
| US-7338722-B2 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |
| CN-1788012-A | Phenyl-pyrazole complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2006-06-14 | — | — | CN | disclosed |
| US-20060024526-A1 | tris(phenylpyrazole) iridium complex; stability | THOMPSON MARK E | 2006-02-02 | — | — | US | disclosed |
| EP-1606296-A2 | PHENYL-PYRAZOLE COMPLEXES OF Ir | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6951694-B2 | Organic light emitting devices with electron blocking layers | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2004-12-16 | — | — | US | disclosed |
| WO-2004085450-A2 | PHENYL-PYRAZOLE COMPLEXES OF IR | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040048101-A1 | Organic light emitting devices with electron blocking layers | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | NR2E3, IK, NR2C2 | NOTUM 3367/4885ALDH1A1 2031/4885MAPK1 3037/4885 |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | EML4, RCOR3, CPNE4 | NOTUM 4244/4885ALDH1A1 630/4885MAPK1 3632/4885 |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | EML4, AFF4, RCOR3 | NOTUM 4245/4885ALDH1A1 664/4885MAPK1 3319/4885 |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | EML4, RNF4, LIG4 | NOTUM 3476/4885ALDH1A1 413/4885MAPK1 3568/4885 |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | EML4, AFF4, RCOR3 | NOTUM 4245/4885ALDH1A1 664/4885MAPK1 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.