Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416945 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL18359303 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL27468547 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL570007 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL10775005 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL10916809 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL7513902 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL22119164 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL3998201 | 0.78 | GAA (0.58) | HPGDMEN1KMT2AGAAPOLB | |
| Hydrochloric Acid SCHEMBL28543626 | 0.77 | GAA (0.57) | HPGDMEN1KMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902400-A | Aromatic derivatives, process for their preparation and their medical use | 保仕健生物科技(上海)有限公司 | 2020-11-06 | — | — | CN | disclosed |