Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468547 | 0.96 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL28534811 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL9284026 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2APKMHPGD | |
| SCHEMBL3998201 | 0.79 | GAA (0.58) | GAAMEN1KMT2APKMHPGD | |
| SCHEMBL10388225 | 0.78 | L3MBTL1 (0.41) | SMN1; SMN2GAA | |
| SCHEMBL10773058 | 0.78 | PKM (0.39) | SMN1; SMN2GAAPKMALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28543626 | 0.77 | GAA (0.57) | GAAMEN1KMT2APKMHPGD | |
| SCHEMBL18359283 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL12725370 | 0.76 | TDP1 (0.42) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL10772470 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2GAAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224094-A2 | 1-Aryl-pyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | claimed |
| EP-0224094-A2 | 1-Aryl-pyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |