Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775005 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL28534811 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL3998201 | 0.80 | GAA (0.58) | GAAMEN1KMT2APKMHPGD | |
| Hydrochloric Acid SCHEMBL28543626 | 0.79 | GAA (0.57) | GAAMEN1KMT2APKMHPGD | |
| SCHEMBL18359283 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL2373014 | 0.76 | KMT2A (0.45) | SMN1; SMN2KMT2APKMHTTALDH1A1 | |
| SCHEMBL2770680 | 0.76 | MEN1 (0.46) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL22119164 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL12725321 | 0.75 | TDP1 (0.43) | SMN1; SMN2GAAMEN1KMT2APKM | |
| Dimethylformamide SCHEMBL28801531 | 0.75 | GAA (0.41) | SMN1; SMN2GAAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229349-C | Pyridine-3-carboxylic acid derivative | PFIZER (US) | 2005-11-30 | — | — | CN | disclosed |
| CN-1495169-A | Pyridine-3-carboxylic acid derivative | — | 2004-05-12 | — | — | CN | disclosed |
| CN-1134442-C | Pyrazolopyrimidinone cGMP PDE5 inhibitor, preparation method and application thereof and intermediate | �������۸��¼��������������ι�˾ | 2004-01-14 | — | — | CN | disclosed |
| CN-1305478-A | Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction | PFIZER (US) | 2001-07-25 | — | — | CN | disclosed |