Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530298 | 0.87 | ENPP2 (0.46) | ENPP2SMPD1MAOBMAOA | |
| SCHEMBL28520513 | 0.83 | CA1 (0.41) | ENPP2SMN1; SMN2 | |
| SCHEMBL28520033 | 0.81 | MAOB (0.41) | ENPP2MAOBSMN1; SMN2MAOA | |
| SCHEMBL28521411 | 0.80 | ENPP2 (0.51) | ENPP2MAOB | |
| SCHEMBL28519536 | 0.77 | USP2 (0.42) | ENPP2 | |
| SCHEMBL28516124 | 0.76 | AR (0.43) | MAOB | |
| SCHEMBL28521446 | 0.75 | NPC1 (0.39) | FFAR1SMN1; SMN2MAOAGAA | |
| SCHEMBL28529096 | 0.75 | NPC1 (0.42) | ENPP2MAOBSMN1; SMN2MAOA | |
| SCHEMBL28512482 | 0.75 | ENPP2 (0.42) | ENPP2MAOB | |
| SCHEMBL29954614 | 0.75 | ENPP2 (0.59) | ENPP2FFAR1SMPD1FFAR4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |