Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512482 | 0.85 | ENPP2 (0.42) | MAOBNR4A2DAOENPP2 | |
| SCHEMBL28520513 | 0.85 | CA1 (0.41) | DAOHDAC6SLC6A2LMNASMN1; SMN2 | |
| SCHEMBL28521411 | 0.84 | ENPP2 (0.51) | MAOBMRGPRX4LMNANPSR1ENPP2 | |
| SCHEMBL28534898 | 0.81 | ENPP2 (0.48) | MAOBMAOASMN1; SMN2ENPP2 | |
| SCHEMBL28908256 | 0.77 | MRGPRX4 (0.41) | MRGPRX4DAOHDAC1HDAC6LMNA | |
| SCHEMBL28529096 | 0.77 | NPC1 (0.42) | MAOBMAOASMN1; SMN2ENPP2 | |
| SCHEMBL28530298 | 0.74 | ENPP2 (0.46) | MAOBMAOALMNAENPP2 | |
| SCHEMBL2562586 | 0.72 | MAOB (0.45) | MAOBMRGPRX4NR4A2DAOSLC6A2 | |
| SCHEMBL4304772 | 0.72 | MAOB (0.63) | MAOBMRGPRX4NR4A2MAOAENPP2 | |
| SCHEMBL28243025 | 0.72 | MAOB (0.44) | MAOBMRGPRX4NR4A2DAOMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |