Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880062 | 1.00 | ABCB1 (0.48) | ABCB1LMNAL3MBTL1RAB9AMEN1 | |
| SCHEMBL23432064 | 1.00 | ABCB1 (0.48) | ABCB1LMNAL3MBTL1RAB9AMEN1 | |
| SCHEMBL23403561 | 0.89 | RAB9A (0.50) | ABCB1RAB9AMEN1KMT2AADRB2 | |
| SCHEMBL21634023 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL18529890 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL29742209 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL29721075 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL28519689 | 0.79 | ADRB2 (0.57) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL21634046 | 0.79 | ADRB2 (0.57) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL30628434 | 0.79 | ADRB2 (0.57) | MEN1KMT2AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424160-A | Novel P62 ligand compound and composition for preventing, ameliorating or treating protein conformational diseases comprising the same | 普罗泰克株式会社 | 2021-02-26 | — | — | CN | disclosed |
| CN-112424159-A | Novel P62 ligand compound and composition for preventing, ameliorating or treating protein conformational diseases comprising the same | 普罗泰克株式会社 | 2021-02-26 | — | — | CN | disclosed |