Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511925 | 0.98 | KDM4E (0.50) | KDM4EHPGDHSD17B10GAATSHR | |
| SCHEMBL29393171 | 0.98 | KDM4E (0.50) | KDM4EHPGDHSD17B10GAATSHR | |
| SCHEMBL23215775 | 0.89 | SRD5A2 (0.46) | KDM4EHPGDHSD17B10GAATSHR | |
| SCHEMBL77380 | 0.83 | KDM4E (0.50) | KDM4EHPGDHSD17B10GAATSHR | |
| SCHEMBL20512834 | 0.81 | CA2 (0.47) | KDM4EHPGDLMNANFKB1POLB | |
| SCHEMBL30568892 | 0.81 | CA2 (0.47) | KDM4EHPGDLMNANFKB1POLB | |
| SCHEMBL10616039 | 0.80 | KDM4E (0.55) | KDM4EHPGDHSD17B10GAATSHR | |
| SCHEMBL154429 | 0.80 | KDM4E (0.55) | KDM4EHPGDHSD17B10GAATSHR | |
| SCHEMBL30816271 | 0.80 | FFAR1 (0.55) | CA2PTPRBTHRB | |
| SCHEMBL9247568 | 0.80 | FFAR1 (0.55) | CA2PTPRBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-112225657-B | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | disclosed |