Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511925 | 0.90 | KDM4E (0.50) | SRD5A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL29393171 | 0.90 | KDM4E (0.50) | SRD5A2KDM4EMAPTHPGDHSD17B10 | |
| Methane SCHEMBL28535162 | 0.89 | KDM4E (0.48) | SRD5A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL7694625 | 0.86 | RARB (0.44) | MAPTHPGDHSD17B10LMNATSHR | |
| SCHEMBL286942 | 0.85 | HTT (0.53) | SRD5A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL30523532 | 0.85 | HTT (0.53) | SRD5A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL77380 | 0.76 | KDM4E (0.50) | SRD5A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL23215776 | 0.76 | PTPRB (0.37) | SRD5A2GAAPTGDR2PTPRBKMT2A | |
| SCHEMBL7559862 | 0.76 | HTT (0.49) | SRD5A2KDM4EMAPTHPGDLMNA | |
| SCHEMBL20512834 | 0.75 | CA2 (0.47) | KDM4EHPGDLMNAPOLBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230061736-A1 | GPR119 AGONISTS | KALLYOPE, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20220153719-A1 | GPR119 AGONISTS | KALLYOPE, INC. | 2022-05-19 | — | — | US | disclosed |
| WO-2021071837-A1 | GPR119 AGONISTS | KALLYOPE, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230061736-A1 | GPR119 AGONISTS | GPR119, GLP1R, GCGR | SRD5A2 1379/4885KDM4E 1450/4885MAPT 2329/4885 |
| US-20220153719-A1 | GPR119 AGONISTS | GPR119, GLP1R, GCGR | SRD5A2 1379/4885KDM4E 1450/4885MAPT 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.