Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533009 | 0.83 | CYP3A4 (0.49) | TSHRNCOA1NCOA3CYP3A4TDP1 | |
| SCHEMBL29669755 | 0.83 | GSTP1 (0.50) | GSTP1MAOALTA4HTSHRNR1H2 | |
| SCHEMBL28569921 | 0.77 | CYP3A4 (0.42) | MAOBMAOAPDK2CYP3A4TDP1 | |
| SCHEMBL9220634 | 0.75 | GSTP1 (0.58) | GSTP1MAOBMAOALTA4HTSHR | |
| SCHEMBL9842743 | 0.74 | GSTP1 (0.57) | GSTP1MAOBMAOALTA4HTSHR | |
| SCHEMBL9220631 | 0.74 | GSTP1 (0.62) | GSTP1MAOBMAOALTA4HTSHR | |
| SCHEMBL28510500 | 0.74 | CYP1A2 (0.40) | TSHRCYP3A4TDP1MEN1KMT2A | |
| SCHEMBL28530516 | 0.74 | CYP3A4 (0.39) | TSHRCYP3A4TDP1ALDH1A1MAPT | |
| SCHEMBL28535167 | 0.74 | ALDH1A1 (0.40) | TSHRCYP3A4TDP1ALDH1A1MAPT | |
| SCHEMBL28292924 | 0.74 | PSMB5 (0.41) | MAOBTSHRCYP3A4TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478627-B | Allylated monophosphine ligand and preparation method thereof | 湖北大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-113666961-B | Preparation method of meta-substituted biaryl tertiary phosphine ligand | 湖北大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-112876507-B | Trisubstituted olefin tertiary phosphine compound and preparation method thereof | 湖北大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114478627-A | Allylation monophosphine ligand and preparation method thereof | 湖北大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113666961-A | Preparation method of meta-substituted biaryl tertiary phosphine ligand | 湖北大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-112876507-A | Trisubstituted olefin tertiary phosphine compound and preparation method thereof | 湖北大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109851635-B | Novel alkylated monophosphine ligand and simple preparation method thereof | 湖北大学 | 2021-03-16 | — | — | CN | disclosed |