Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909678 | 0.83 | CHRM5 (0.42) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL22040163 | 0.75 | EED (0.48) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL16309063 | 0.75 | L3MBTL1 (0.47) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL25143376 | 0.71 | L3MBTL1 (0.60) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| Hydrochloric Acid SCHEMBL2349039 | 0.69 | OPRD1 (0.39) | IDO1CXCR2 | |
| SCHEMBL29855727 | 0.68 | CHRM5 (0.40) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL23323106 | 0.68 | CHRM5 (0.44) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL31444531 | 0.67 | MEN1 (0.43) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL22455759 | 0.67 | MEN1 (0.43) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL31738967 | 0.67 | MEN1 (0.43) | CHRM5CHRM3CHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |