SCHEMBL28535291

SCHEMBL28535291

Nc1ccccc1-c1cc(Oc2ccccc2C(=O)c2ccccc2)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
GAA P10253 2/20 0.50
F10 P00742 1/20 0.46
POLB P06746 2/20 0.44
MAPK1 P28482 2/20 0.44
PYGL P06737 1/20 0.44
CTNNB1 P35222 1/20 0.43
ELANE P08246 2/20 0.42
HDAC3 O15379 1/20 0.41
BRAF P15056 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29555994 1.00 MAPT (0.50) MAPTGAAF10POLBMAPK1
SCHEMBL29363963 0.92 MAPT (0.50) MAPTGAAF10POLBMAPK1
SCHEMBL28349990 0.92 MAPT (0.50) MAPTGAAF10POLBMAPK1
SCHEMBL28338529 0.84 MAPK1 (0.50) MAPTGAAF10POLBMAPK1
SCHEMBL9297643 0.83 MAPT (0.49) MAPTGAAF10POLBMAPK1
SCHEMBL28338598 0.81 MAPT (0.49) MAPTGAAF10POLBMAPK1
SCHEMBL3455047 0.79 CTNNB1 (0.56) MAPTGAAPOLBMAPK1CTNNB1
SCHEMBL28499859 0.78 MAPT (0.65) MAPTGAAPOLBMAPK1CTNNB1
SCHEMBL27787738 0.78 MAPT (0.45) MAPTGAAPOLBMAPK1CTNNB1
SCHEMBL8609529 0.78 PBRM1 (0.54) MAPTGAAF10POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112512792-A Laminate and method for producing laminate 东洋纺株式会社 2021-03-16 CN disclosed