Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107636 | 0.82 | TDP1 (0.59) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL9107624 | 0.82 | TDP1 (0.59) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL28530745 | 0.81 | TDP1 (0.52) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL19144225 | 0.78 | PTGER2 (0.57) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2508320 | 0.77 | LGMN (0.41) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL20411424 | 0.74 | TP53 (0.55) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL7434354 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL17977269 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL8260150 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL9892984 | 0.73 | POLB (0.54) | ALDH1A1KMT2AMEN1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185452-A | Urea derivatives or pharmaceutically acceptable salts thereof | 杏林制药株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-107849049-B | Urea derivatives or pharmaceutically acceptable salts thereof | 杏林制药株式会社 | 2021-03-16 | — | — | CN | disclosed |