Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535646 | 0.89 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL31401930 | 0.89 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL21331793 | 0.88 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| Benzene SCHEMBL28241676 | 0.88 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| Fluoride SCHEMBL27600467 | 0.88 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL28713393 | 0.88 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL1299793 | 0.86 | ERN1 (0.45) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL27565932 | 0.84 | LMNA (0.56) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL4735464 | 0.83 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| 1,2-Dichlorobenzene SCHEMBL27565814 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424160-A | Novel P62 ligand compound and composition for preventing, ameliorating or treating protein conformational diseases comprising the same | 普罗泰克株式会社 | 2021-02-26 | — | — | CN | disclosed |